According to Wikipedia, this is quite the race of firsts:
The 2008 election is particularly notable because it is the first time in U.S. history that two sitting senators will run against each other for president, and because it is the first time an African American is a presidential nominee for a major party, as well as the first time both major candidates were born outside the continental United States—Hawaii for Obama and the Panama Canal Zone for McCain. Since the Republican nominee for vice-president is a woman, the eventual winning ticket is very likely to be historic, as neither an African American nor a female has achieved either office. Also, the Republican presidential candidate, John McCain, would be the oldest first-term president and the Democratic nominee for vice-president, Joe Biden, would be the first Roman Catholic vice president.I had to think carefully before I could decide if Wikipedia needed a capital or not. Teaching is making me a little less bright, methinks.